BIG Breast International Group
We will find a cure for breast cancer through global research and collaboration.


The Suppression of Ovarian Function Trial (SOFT) is a phase III trial evaluating the role of ovarian suppression and the role of exemestane as adjuvant therapies for premenopausal women with endocrine responsive breast cancer.

Coordinating group: IBCSG

Patients accrual
Start date: August 2003
Closure date: January 2011
Target nr. of patients: 3000
Final accrual: 3066

Reason for closure: reached target accrual Identifier: NCT00066690

To learn more, visit:

Scroll to top

Contact us

Breast International Group (BIG)-aisbl Blvd de Waterloo 121 B-1000 Brussels | Belgium VAT BE 0468 176 240