BIG Breast International Group
We will find a cure for breast cancer through global research and collaboration.


The Randomised EuropeAn Celecoxib Trial (REACT) is a phase III multicentre double blind randomised trial of celecoxib versus placebo in primary breast cancer patients.

Coordinating groups: ICCG / GBG

Patients accrual
Study re-opened: January 2007
Closure date: October 2012
Target nr. of patients: 2590
Final accrual: 2590

Reason for closure: reached target accrual

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Breast International Group (BIG)-aisbl Blvd de Waterloo 121 B-1000 Brussels | Belgium VAT BE 0468 176 240