BIG Breast International Group
We will find a cure for breast cancer through global research and collaboration.

BIG 1-00 p53

BIG 1-00 p53 is the first prospective intergroup translational research trial assessing the potential predictive value of p53 using a functional assay in yeast in patients with locally advanced/inflammatory or large operable breast cancer prospectively randomised to a taxane versus a non-taxane regime.

Coordinating group: EORTC BCG

Patients accrual
Start date: March 2001
Closure date: November 2006
Target nr. of patients: 1850
Final accrual: 1856

Status: closed

ClinicalTrials.gov Identifier: NCT00017095

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Breast International Group (BIG)-aisbl Blvd de Waterloo 121 B-1000 Brussels | Belgium VAT BE 0468 176 240