BIG Breast International Group
We will find a cure for breast cancer through global research and collaboration.


The Breast International Group (BIG) is an international not-for-profit organisation that represents the largest global network of academic groups dedicated to breast cancer research. 30+ clinical trials are run or under development under the BIG umbrella at any one time.

The Breast International Group (BIG) is seeking a full-time, experienced Clinical Trials Project Manager, to be based in its headquarters in Brussels, Belgium.

BIG is an international non-profit organization that represents the largest global network – over 50 countries, across 6 continents – of academic groups dedicated to breast cancer research. Its mission is to facilitate and accelerate breast cancer research internationally. 


Job summary:

As an experienced Clinical Trials Project Manager in the Scientific Operations Department at BIG Headquarters (HQ), you will focus on the set-up and execution of international clinical studies (Phase  II / III) or related research projects with a variety of partners. You will be based in Brussels, Belgium, report to a Project Management Leader (line manager) and the Scientific Director, and will be engaged in the following types of activities:


  • Serve as a main study contact between multiple partners, including BIG member groups, pharmaceutical industry partners, and a variety of vendors for specific clinical trials
  • Coordinate BIG HQ responsibilities for individual clinical trials, e.g.,
    • conduct of group surveys / site feasibility
    • set up of study governance committees and related documentation
    • coordination of governance committees and working groups and their meetings (including taking minutes)
    • development of study contracts and budgets in collaboration with the Legal and Finance departments,
    • prepare, manage and follow-up on meetings between partners (including taking minutes)
    • Prepare and/or review study documents and communications
    • Assist in preparing reports and articles if needed
    • Assist in preparation and follow-up of study-related grants if needed
    • other scientific operations activities as needed
    • ensure that BIG principles and processes are adhered to, under the guidance of Project Management Leaders


  • Organise internal team meetings
  • Maintain BIG HQ study / project files
    • Assist Project Management Leaders as needed
    • As part of a project management team, contribute to the improvement of all processes and procedures as well as all related documentation in BIG HQ 

Qualifications sought:

  • Academic degree, preferably in a (para)medical discipline
    • Experience in the set-up and management of all operational aspects of clinical trials (in academia, industry, or CRO)
    • In-depth knowledge of methodologies, regulations and procedures related to clinical trials
    • Experience in oncology clinical trials a plus
    • Possess strong analytical skills and highly organized project management abilities, keeping an eye on both detail, while maintaining a broad overview
    • Ability to:
      • work effectively in multicultural teams within BIG headquarters and the BIG network, and across organisational boundaries, respecting differences between people from a variety of linguistic and cultural backgrounds
      • learn, interpret and apply a variety of complex policies and procedures with minimal guidance
      • accurately and professionally process a high volume of correspondence, documents and other often sensitive and confidential information
      • maintain a high level of poise and professionalism while coordinating a diverse variety of daily and special project deadlines simultaneously
      • Native or native-like written and spoken English; French, Dutch or other languages a plus
      • A high level of integrity and sense of responsibility and professionalism


What we offer:

The opportunity to contribute to innovative, practice-changing cancer research.

A stimulating international environment and a competitive salary and benefits package.


Please send your CV and cover letter to:

Breast International Group-aisbl                         

HR Department

Blvd de Waterloo 76                               

B-1000 Brussels                                                  


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Contact us

Breast International Group (BIG)-aisbl Blvd de Waterloo 121 B-1000 Brussels | Belgium VAT BE 0468 176 240